| 產品名稱 | Erlotinib hydrochloride - OSI 774 |
| 產品貨號 | Axon 1128 CAS [183319-69-9] MF C22H23N3O4.HClMW 429.90 Purity: 99% Soluble in DMSO Description EGFR?inhibitor; Erlotinib inhibits EGFR tyrosine kinase autophosphorylation by inhibition of the intracellular domain. Studies in cell lines and enzyme assays have both shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl References Certificates Categories Extra info J.R. Johnson et al.?Approval Summary for Erlotinib for Treatment of Patients with Locally Advanced or Metastatic Non–Small Cell Lung Cancer after Failure of at Least One Prior Chemotherapy Regimen.?Clin. Can. Res.?2005, 11, 6414-6421. ? J. Porter et al.?A dose escalation and pharmacokinetic (PK) trial of weekly docetaxel combined with daily erlotinib in adult cancer patients.?J. Clin. Oncol.2004, 22, 14S, 2119. Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology EGFR JAK-STAT RTK class I; EC 2.7.10.1 EGFR tyrosine kinase inhibitor Chemical name [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine hydrochloride Parent CAS No. [183321-74-6] Order Size Unit Price Stock 10 mg €70.00 In Stock |
| 產品價格 | 現貨詢價，電話：010-67529703 |
| 產品規格 | |
| 產品品牌 | axonmedchem |
| 產品概述 | |
| 產品詳情 |
Erlotinib hydrochloride - OSI 774Axon 1128 CAS [183319-69-9] MF C22H23N3O4.HCl
Description
EGFR?inhibitor; Erlotinib inhibits EGFR tyrosine kinase autophosphorylation by inhibition of the intracellular domain. Studies in cell lines and enzyme assays have both shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl
EGFR tyrosine kinase inhibitor
Chemical name[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine hydrochloride Parent CAS No.[183321-74-6] |
| 產品資料 |
