| 產品名稱 | UNC 2250 |
| 產品貨號 | Axon 2346 CAS [1493694-70-4] MF C24H36N6O2MW 440.58 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Potent Mer kinase inhibitor (in vitro IC50 values 1.7 nM, 270 nM, and 100 nM for Mer, Axl, and Tyro3 RTKs, respectively) with promising selectivity and PK properties. UNC 2250 efficiently inhibited both steady state and ligand-stimulated phosphorylation of Mer, and confirmed functional antitumor activity by exhibiting potential to reduced colony-forming in both rhabdoid tumor cells and NSCLC cells. KEYWORDS:?UNC 2250 | supplier | Mer Inhibitor | UNC2250 | CAS [1493694-70-4] | Gas6 | Mer | TAM | RTK | Axl | Tyro3 | antitumor | rhabdoid | NSCLC | lung cancer |
| 產品價格 | 現貨詢價，電話：010-67529703 |
| 產品規格 | |
| 產品品牌 | axonmedchem |
| 產品概述 | |
| 產品詳情 |
UNC 2250Axon 2346 CAS [1493694-70-4] MF C24H36N6O2
DescriptionPotent Mer kinase inhibitor (in vitro IC50 values 1.7 nM, 270 nM, and 100 nM for Mer, Axl, and Tyro3 RTKs, respectively) with promising selectivity and PK properties. UNC 2250 efficiently inhibited both steady state and ligand-stimulated phosphorylation of Mer, and confirmed functional antitumor activity by exhibiting potential to reduced colony-forming in both rhabdoid tumor cells and NSCLC cells. KEYWORDS:?UNC 2250 | supplier | Mer Inhibitor | UNC2250 | CAS [1493694-70-4] | Gas6 | Mer | TAM | RTK | Axl | Tyro3 | antitumor | rhabdoid | NSCLC | lung cancer
Potent Mer kinase inhibitor with promising selectivity and PK properties.
Chemical name(1r,4r)-4-(2-(butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-ylamino)cyclohexanol Parent CAS No.[1493694-70-4] |
| 產品資料 |
