| 產品名稱 | Recombinant Human DKK-2 (Carrier-free), Tonbo Biosciences |
| 產品貨號 | 21-7101-U100 |
| 產品價格 | 現貨詢價，電話：010-67529703 |
| 產品規格 | |
| 產品品牌 | vwr |
| 產品概述 | |
| 產品詳情 |
The DKK (Dickkopf) family of secreted proteins includes DKK-1 through -4, and a related protein, Soggy (DKK-11). Like DKK-1, DKK-2 can act as an antagonist of the Wnt signaling pathway, forming inhibitory complexes with Wnt co-receptor LRP6 and Kremen-2. However, when LRP6 is overexpressed direct binding of DKK-2 activates canonical Wnt signaling. DKK-2 is expressed in bone, eye and other mesenchymal tissues.
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