| 產品名稱 | Recombinant Human E-selectin (Carrier-free) |
| 產品貨號 | 21-7178-U500 |
| 產品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產品規(guī)格 | |
| 產品品牌 | vwr |
| 產品概述 | |
| 產品詳情 |
E-selectin (CD62E) is a member of the calcium-dependent selectin family. E-selectin, a cell adhesion surface glycoprotein, is also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1), or leukocyte-endothelial cell adhesion molecule 2 (LECAM2). E-selectin is expressed on cytokine activated endothelial cells playing a critical role in inflammation. E-selectin recognizes and binds to sialylated carbohydrates present on the surface proteins expressed by neutrophils, monocytes, eosinophils, memory-effector T-like lymphocytes, and natural killer cells. Macrophage release of cytokines induces the over-expression of E-selectin on endothelial cells of nearby blood vessels. Along with other selectins, E-selectin recruits circulating leukocytes to the site of inflammation. E-selectin is associated with metastatic dissemination of tumor cells by facilitating their escape from the location of the primary tumor. Recombinant Human E-selectin comprises the extracellular signaling domain of the E-selectin protein.
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| 產品資料 |
