| 產(chǎn)品名稱 | PF 06447475 |
| 產(chǎn)品貨號(hào) | Axon 2546 CAS [1527473-33-1] MF C17H15N5OMW 305.33 Purity: 99% Soluble in DMSO Description Highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor (IC50 value 3 nM); an exceptional tool compound to study the function of LRRK2 PF 06447475 mitigates both neurodegeneration and neuroinflammation associated with G2019S-LRRK2 expression by LRRK2 kinase inhibition in rats. KEYWORDS: PF 06447475 | supplier | LRRK2 inhibitor | PF06447475 | CAS [1527473-33-1] | LRRK2 | Inhibitor | neurodegeneration | neuroinflammation | Parkinson's |Huntington's | PD | dopamine | synuclein |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
PF 06447475Axon 2546 CAS [1527473-33-1] MF C17H15N5O
DescriptionHighly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor (IC50 value 3 nM); an exceptional tool compound to study the function of LRRK2 PF 06447475 mitigates both neurodegeneration and neuroinflammation associated with G2019S-LRRK2 expression by LRRK2 kinase inhibition in rats. KEYWORDS: PF 06447475 | supplier | LRRK2 inhibitor | PF06447475 | CAS [1527473-33-1] | LRRK2 | Inhibitor | neurodegeneration | neuroinflammation | Parkinson's |Huntington's | PD | dopamine | synuclein
Potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor
Chemical name3-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile Source informationPfizer compound; Sold for research purposes under agreement from Pfizer Inc.Parent CAS No.[1527473-33-1] |
| 產(chǎn)品資料 |
