| 產品名稱 | SPL-B - Spindlactone B |
| 產品貨號 | Axon 2474 CAS [1465248-60-5] MF C27H22N2O5MW 454.47 Purity: 98% Soluble in 0.1N HCl(aq) and DMSO Description Orally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells. SPL significantly inhibits mitosis in cancer cells and suppresses in vivo tumor growth. KEYWORDS: SPL-B | supplier | TACC3 inhibitor | Spindlactone B | SPLB | CAS [1465248-60-5] | microtubules | MTs | TACC | Inhibitor | proteins | mitotic spindle | assembly | mitosis | centrosomal | TOGp | Aurora A | coumarin | cell-cycle regulation | differentiation |
| 產品價格 | 現貨詢價，電話：010-67529703 |
| 產品規格 | |
| 產品品牌 | axonmedchem |
| 產品概述 | |
| 產品詳情 |
SPL-B - Spindlactone BAxon 2474 CAS [1465248-60-5] MF C27H22N2O5
DescriptionOrally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells. SPL significantly inhibits mitosis in cancer cells and suppresses in vivo tumor growth. KEYWORDS: SPL-B | supplier | TACC3 inhibitor | Spindlactone B | SPLB | CAS [1465248-60-5] | microtubules | MTs | TACC | Inhibitor | proteins | mitotic spindle | assembly | mitosis | centrosomal | TOGp | Aurora A | coumarin | cell-cycle regulation | differentiation
Inhibitor of TACC3 that inhibits nucleation of centrosome microtubules
Chemical name8'-((ethyl(pyridin-4-ylmethyl)amino)methyl)-7'-hydroxy-2H,2'H-3,4'-bichromene-2,2'-dione Parent CAS No.[1465248-60-5] |
| 產品資料 |
