| 產品名稱 | ML364 |
| 產品貨號 | Axon 2678 CAS [1991986-30-1] MF C24H18F3N3O3S2MW 517.54 Purity: 99% Soluble in DMSO Description ML364, a small molecule inhibitor of the deubiquitinase USP2 (IC50 value of 1.1 μM), induced an increase in cellular cyclin D1 degradation and caused cell cycle arrest. Consistent with the role of cyclin D1 in DNA damage response, ML364 also caused a decrease in homologous recombination-mediated DNA repair. These effects by a small molecule inhibitor support a key role for USP2 as a regulator of cell cycle, DNA repair, and tumor cell growth. KEYWORDS: ML364 | supplier | USP2 inhibitor | ML 364 | ML-364 | CAS [1991986-30-1] | Non Selective (Ubiquitin peptides) | Deubiquitinase | Inhibitor | Enzymes |
| 產品價格 | 現貨詢價，電話：010-67529703 |
| 產品規格 | |
| 產品品牌 | axonmedchem |
| 產品概述 | |
| 產品詳情 |
ML364Axon 2678 CAS [1991986-30-1] MF C24H18F3N3O3S2
DescriptionML364, a small molecule inhibitor of the deubiquitinase USP2 (IC50 value of 1.1 μM), induced an increase in cellular cyclin D1 degradation and caused cell cycle arrest. Consistent with the role of cyclin D1 in DNA damage response, ML364 also caused a decrease in homologous recombination-mediated DNA repair. These effects by a small molecule inhibitor support a key role for USP2 as a regulator of cell cycle, DNA repair, and tumor cell growth. KEYWORDS: ML364 | supplier | USP2 inhibitor | ML 364 | ML-364 | CAS [1991986-30-1] | Non Selective (Ubiquitin peptides) | Deubiquitinase | Inhibitor | Enzymes
Inhibitor of the deubiquitinase USP2
Chemical name2-(4-Methylphenylsulfonamido)-N-(4-phenylthiazol-2-yl)-4-(trifluoromethyl)benzamide Parent CAS No.[1991986-30-1] |
| 產品資料 |
